Relationships Between Adverse Childhood Experiences and Health Status in Systemic Lupus Erythematosus.

ABSTRACT:

Objective

Adverse childhood experiences (ACEs) are associated with poor adult health and immune dysregulation. The impact of ACEs on patients with autoimmune disease is unknown. The present study was undertaken to compare the prevalence of ACEs in patients with systemic lupus erythematosus (SLE) to a population-based survey estimate and to investigate relationships between ACEs and SLE outcomes.

Methods

Data derived from the California Lupus Epidemiology Study (CLUES), a sample of adult patients with SLE. Participants completed a 10-item ACE questionnaire covering 3 domains (abuse, neglect, household challenges). We estimated ACE prevalence in 269 CLUES participants compared to geographically matched respondents from the 2015 California Behavioral Risk Factor Surveillance Sy

SUBMITTER: DeQuattro K 

PROVIDER: S-EPMC6842031 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature