Stability and reproducibility of computed tomography radiomic features extracted from peritumoral regions of lung cancer lesions.

ABSTRACT: PURPOSE:Recent efforts have demonstrated that radiomic features extracted from the peritumoral region, the area surrounding the tumor parenchyma, have clinical utility in various cancer types. However, as like any radiomic features, peritumoral features could also be unstable and/or nonreproducible. Hence, the purpose of this study was to assess the stability and reproducibility of computed tomography (CT) radiomic features extracted from the peritumoral regions of lung lesions where stability was defined as the consistency of a feature by different segmentations, and reproducibility was defined as the consistency of a feature to different image acquisitions. METHODS:Stability was measured utilizing the "moist run" dataset and reproducibility was measured utilizing the Reference Image Data

SUBMITTER: Tunali I 

PROVIDER: S-EPMC6842054 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature