Prenatal lead exposure and childhood executive function and behavioral difficulties in project viva.

ABSTRACT:

Background

Lead is an established neurotoxicant and early life exposure to lead is associated with detrimental impacts on IQ and several neurobehavioral domains. Less is known, however, about effects of prenatal lead exposure below 5 μg/dL on executive function and on social, emotional and self-regulatory behaviors in childhood.

Objectives

To examine the association between prenatal lead exposure and childhood executive function and social, emotional and self-regulatory behaviors.

Methods

We included 1006 mother-child pairs from the Project Viva prospective pre-birth cohort. We measured prenatal maternal lead in second-trimester erythrocytes. In mid-childhood (median 7.7 years), parents and teachers rated executive function related behaviors using the Behavior Rating

SUBMITTER: Fruh V 

PROVIDER: S-EPMC6842061 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature