Prospectively collected lifestyle and health information as risk factors for white matter hyperintensity volume in stroke patients.

ABSTRACT: Most studies of white matter hyperintensity volume (WMHV) in stroke patients lack reliable information on antecedent exposure to vascular risk factors. By leveraging prospective cohort data, we explored associations between lifestyle and health factors assessed 1 year prior to stroke and WMHV in individuals who experienced an ischemic stroke. This analysis was nested within two large prospective studies of initially healthy individuals. Information on lifestyle factors and health conditions was collected prior to the stroke event through annual or biannual questionnaires. For individuals who experienced their first confirmed ischemic stroke and had available magnetic resonance imaging, we measured WMHV using a validated semiautomated method. Linear regression was used to explore associatio

SUBMITTER: Rist PM 

PROVIDER: S-EPMC6842429 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature