Trait-like variants in human functional brain networks.

ABSTRACT: Resting-state functional magnetic resonance imaging (fMRI) has provided converging descriptions of group-level functional brain organization. Recent work has revealed that functional networks identified in individuals contain local features that differ from the group-level description. We define these features as network variants. Building on these studies, we ask whether distributions of network variants reflect stable, trait-like differences in brain organization. Across several datasets of highly-sampled individuals we show that 1) variants are highly stable within individuals, 2) variants are found in characteristic locations and associate with characteristic functional networks across large groups, 3) task-evoked signals in variants demonstrate a link to functional variation, and 4) i

SUBMITTER: Seitzman BA 

PROVIDER: S-EPMC6842602 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature