A preliminary study of association between adolescent estradiol level and dorsolateral prefrontal cortex activity during emotion regulation.

ABSTRACT: Non-human primate models have been useful in clarifying estradiol's role in cognitive processing. These animal studies indicate estradiol impacts cognitive processes supported by regions within dorsolateral prefrontal cortex (DLPFC). Although human functional neuroimaging studies have begun to find similar relationships between estradiol in women for some forms of 'cold' cognitive control, to date no studies have examined the relationship between estradiol and DLPFC function in the context of active attempts to regulate one's emotions. Here, we asked whether peripheral 17-beta estradiol levels in adolescent girls in different pubertal developmental stages (age = 14.9 years ± 1.74) were related to engagement of DLPFC regions during the use of a cognitive strategy for regulating emotion know

SUBMITTER: Chung YS 

PROVIDER: S-EPMC6842698 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature