Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae causing invasive diseases in China: a meta-analysis.

ABSTRACT:

Background

To summarize information about invasive pneumococcal disease (IPD) among children in mainland China.

Methods

Sixteen eligible studies were included in this systematic review and the random effect model was used to estimate the pool prevalence of IPD.

Results

The most predominant serotypes circulating in children were 19F (27.7, 95% confidence interval (95% CI): 17.7-37.6%), 19A (21.2%, 16.4-26.1%), 14 (16.5%, 12.8-20.1%), 6B (8.6%, 5.2-10.8%) and 23F (7.3%, 5.2-9.5%). The serotype coverage of the available pneumococcal conjugate vaccines PCV7, PCV10, and PCV13 was 60.8% (52.5-69.4%), 65.1% (57.7-72.4%), and 90.0% (87.1-92.8%), respectively. The pooled antibiotic resistance rates of Streptococcus pneumoniae revealed a resistance to penicillin prevalence rate

SUBMITTER: Fu J 

PROVIDER: S-EPMC6844036 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature