Fluorescent Porous Silica Microspheres for Highly and Selectively Detecting Hg²⁺ and Pb²⁺ Ions and Imaging in Living Cells.

ABSTRACT: In this work, SiO₂ microspheres were first prepared by a conventional Stöber method and then etched by NaOH solution to obtain porous ones. By tuning the degree of etching, specific surface area of SiO₂ microspheres could be controlled. Then, small fluorescent molecules are synthesized and incorporated onto the surface and/or pores of the SiO₂ via layer-by-layer reaction to obtain fluorescent microspheres, namely, SiO₂-NH₂-BODIPY (SiNBB), SiO₂-NH₂-BODIPY-indole-benzothiazole (SiNBIT), and SiO₂-NH₂-BODIPY-indole-benzoxazole (SiNBIO). The as-prepared microspheres SiNBB exhibit highly sensitive and selective recognition ability for Hg²⁺ and Pb²⁺. When SiNBB encounters Hg

SUBMITTER: Sun W 

PROVIDER: S-EPMC6844105 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature