Long-Term Impact of Cytomegalovirus Serologic Status on Lung Transplantation in the United States.

ABSTRACT:

Background

Cytomegalovirus (CMV) infection has been associated with poor outcomes after solid organ transplantation. The long-term impact of donor and recipient CMV serological status on lung transplant outcomes remains unclear. Accordingly, we evaluated the impact of donor and recipient CMV status on long-term patients as well as allograft survival after single (SLT) and double lung transplantation (BLT).

Methods

The Scientific Registry of Transplant Recipients was used to track all adult lung transplants in United States from May 2005 to June 2016. Patient mortality and bronchiolitis obliterans syndrome were determined up to 5 years using Cox proportional hazards modeling. Additionally, landmark analysis was performed conditional on survival at 1 year.

Results

Compa

SUBMITTER: Kurihara C 

PROVIDER: S-EPMC6844363 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature