Neural substrates for anticipation and consumption of social and monetary incentives in depression.

ABSTRACT: Depression has been reliably associated with abnormalities in the neural representation of reward and loss. However, most studies have focused on monetary incentives; fewer studies have considered neural representation of social incentives. A direct comparison of non-social and social incentives within the same study would establish whether responses to the different incentives are differentially affected in depression. The functional magnetic resonance imaging study presented here investigated the neural activity of individuals with subthreshold depression (SD) and healthy controls (HCs) while they participated in an incentive delay task offering two types of reward (monetary gain vs social approval) and loss (monetary loss vs social disapproval). Compared to HCs, individuals with SD show

SUBMITTER: He Z 

PROVIDER: S-EPMC6847340 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature