Disease monitoring strategies in inflammatory bowel diseases: What do we mean by "tight control"?

ABSTRACT: In recent years, there has been a critical change in treatment paradigms in inflammatory bowel diseases (IBD) triggered by the arrival of new effective treatments aiming to prevent disease progression, bowel damage and disability. The insufficiency of symptomatic disease control and the well-known discordance between symptoms and objective measures of disease activity lead to the need of reviewing conventional treatment algorithms and developing new concepts of optimal therapeutic strategy. The treat-to-target strategies, defined by the selecting therapeutic targets in inflammatory bowel disease consensus recommendation, move away from only symptomatic disease control and support targeting composite therapeutic endpoints (clinical and endoscopical remission) and timely assessment. Emerging

SUBMITTER: Gonczi L 

PROVIDER: S-EPMC6848014 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature