Associations between socioeconomic status, psychosocial stress, and urinary levels of 8-iso-prostaglandin-F_2α during pregnancy in Puerto Rico.

ABSTRACT:

Background

Lower socioeconomic status (SES) and psychosocial stress during pregnancy have been associated with adverse birth outcomes. While hypothalamic-pituitary-axis activation is thought to be the primary driver, oxidative stress may also be involved mechanistically. We used data from the Puerto Rico Testsite for Exploring Contamination Threats (PROTECT) cohort (N=476) to examine associations between self-reported psychosocial stress measures, SES indicators, and urinary oxidative stress biomarker concentrations, hypothesizing that women with lower SES and increased psychosocial stress would have elevated oxidative stress biomarkers.

Methods

Maternal age, education, marital status, insurance status, alcohol use and smoking status were obtained via self-reported questionn

SUBMITTER: Eick SM 

PROVIDER: S-EPMC6848779 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature