Brain activity mediators of PTSD symptom reduction during real-time fMRI amygdala neurofeedback emotional training.

ABSTRACT: Self-regulation of brain activation with real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) is emerging as a promising treatment for psychiatric disorders. The association between the regulation and symptom reduction, however, has not been consistent, and the mechanisms underlying the symptom reduction remain poorly understood. The present study investigated brain activity mediators of the amygdala rtfMRI-nf training effect on combat veterans' PTSD symptom reduction. The training was designed to increase a neurofeedback signal either from the left amygdala (experimental group; EG) or from a control region not implicated in emotion regulation (control group; CG) during positive autobiographical memory recall. We employed a structural equation model mapping analysis to

SUBMITTER: Misaki M 

PROVIDER: S-EPMC6849428 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature