A case of persistent fever, cutaneous manifestations and pulmonary and splenic nodules: clinical experience and a literature review.

ABSTRACT: Pyoderma gangrenosum (PG) is a rare and recurrent ulcerating, non-infectious, inflammatory dermatosis, with occasional concomitant extracutaneous manifestations. The pathogenesis and aetiology of PG are unknown. Moreover, early diagnosis is challenging because there are several visceral manifestations that may occur prior to the skin findings, such that misdiagnosis of PG as an infection is common. Here, we present a case of PG in which pulmonary and spleen lesions preceded the cutaneous manifestations. The correct diagnosis was made 6 months after multiple nodules were detected in the lung and spleen, based on the development of skin wound ulcers. To the best of our knowledge, this is the first report of PG in which pulmonary and splenic involvement preceded the appearance of skin lesions

SUBMITTER: Xu P 

PROVIDER: S-EPMC6849849 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature