In search of the most cost-effective monitoring strategy for vestibular schwannoma: A decision analytical modelling study.

ABSTRACT:

Objectives

To assess the cost-effectiveness of frequently used monitoring strategies for vestibular schwannoma (VS).

Design

A state transition model was developed to compare six monitoring strategies for patients with VS: lifelong annual monitoring; annual monitoring for the first 10 years after diagnosis; scanning at 1-5, 7, 9, 12, 15 years after diagnosis and subsequently every 5 years; a personalised monitoring strategy for small and large tumours; scanning at 1, 2 and 5 years after diagnosis and no monitoring. Input data were derived from literature and expert opinion. Quality-adjusted life years (QALYs) and healthcare costs of each strategy were modelled over lifetime. Net monetary benefits (NMBs) were calculated to determine which strategy provided most value for money

SUBMITTER: Scholte M 

PROVIDER: S-EPMC6850121 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature