Immunity-targeted approaches to the management of chronic and recurrent upper respiratory tract disorders in children.

ABSTRACT:

Background

Upper respiratory tract infections (URTIs), including rhinitis, nasopharyngitis, tonsillitis and otitis media (OM), comprise of 88% of total respiratory infections, especially in children. Therefore effective prevention and treatment of RTIs remain a high priority worldwide. Preclinical and clinical data highlight the rationale for the use and effectiveness of immunity-targeted approaches, including targeted immunisations and non-specific immunomodulation in the prevention and management of recurrent upper RTIs.

Objective of review

The idea of this review was to summarise the current evidence and address key questions concerning the use of conservative and immunity-targeted approaches to recurrent and chronic URTIs, with a focus on the paediatric population.

Se

SUBMITTER: Feleszko W 

PROVIDER: S-EPMC6850198 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature