Brain natriuretic peptide reflects individual variation in hydration status in hemodialysis patients.

ABSTRACT:

Introduction

Fluid management in hemodialysis patients is a controversial topic. Brain natriuretic peptide (BNP) is secreted from the heart in response to volume overload, and may be a marker of overhydration in hemodialysis patients. Our aim was to investigate the correlation between BNP and overhydration in a cohort of hemodialysis patients, and to find out whether BNP and overhydration correlate in repeated measurements within individuals with elevated BNP.

Methods

The study was prospective, observational, and had a cross-sectional part and a longitudinal follow-up. The distribution of BNP was investigated in a cohort of 64 hemodialysis patients. Blood samples and bioimpedance spectroscopy measurements were performed before midweek dialysis. Subsequently, 11 study partici

SUBMITTER: Stenberg J 

PROVIDER: S-EPMC6850372 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature