Improved survival following splenectomy combined with curative treatments for hepatocellular carcinoma in Child B patients: A propensity score matching study.

ABSTRACT:

Aims

To explore the benefits of curative treatments (liver resection or local ablation) combined with splenectomy for patients with hepatocellular carcinoma (HCC) and Child grade B liver function.

Methods

We reviewed 245 patients with Child grade B liver function who underwent treatment with curative intent for HCC. Among these patients, 116 patients underwent curative treatment combined with splenectomy (the splenectomy group); the other 129 patients only underwent curative treatment (the non-splenectomy group). A one-to-one matching produced 95 paired patients, perioperative and oncological outcomes were compared, and liver function changes were reassessed 1 year later.

Results

The perioperative liver failure rates were 7.4% and 6.3% (P = 1.000) and the 90-day morta

SUBMITTER: Pei Y 

PROVIDER: S-EPMC6850487 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature