A consensus redefinition of transfusion-related acute lung injury.

ABSTRACT:

Background

Transfusion-related acute lung injury (TRALI) is a serious complication of blood transfusion and is among the leading causes of transfusion-related morbidity and mortality in most developed countries. In the past decade, the pathophysiology of this potentially life-threatening syndrome has been increasingly elucidated, large cohort studies have identified associated patient conditions and transfusion risk factors, and preventive strategies have been successfully implemented. These new insights provide a rationale for updating the 2004 consensus definition of TRALI.

Study design and methods

An international expert panel used the Delphi methodology to develop a redefinition of TRALI by modifying and updating the 2004 definition. Additionally, the panel reviewed issu

SUBMITTER: Vlaar APJ 

PROVIDER: S-EPMC6850655 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature