Treatment patterns and healthcare resource utilization in patients with FLT3-mutated and wild-type acute myeloid leukemia: A medical chart study.

ABSTRACT:

Objectives

To assess real-world treatment patterns and healthcare resource utilization (HRU) among patients with FLT3-mutated (FLT3^mut ) and FLT3-wild-type (FLT3^wt ) acute myeloid leukemia (AML).

Methods

Data were abstracted from medical charts of patients with AML from 10 countries. Patients were grouped based on their FLT3 mutation status, age (18-64 or ≥65), and whether they were newly diagnosed (ND) or relapsed/refractory (R/R).

Results

Charts of 1027 AML patients were included (183 FLT3^mut 18-64 ND; 136 FLT3^mut ≥65 ND; 181 FLT3^mut R/R; 186 FLT3^wt 18-64 ND; 159 FLT3^wt ≥65 ND; 182 FLT3^wt R/R). Substantial heterogeneity was observed in treatment patterns for AML. Among ND patient

SUBMITTER: Griffin JD 

PROVIDER: S-EPMC6850763 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature