TDCS to the left DLPFC modulates cognitive and physiological correlates of executive function in a state-dependent manner.

ABSTRACT:

Background

The use of transcranial Direct Current Stimulation (tDCS) to study anatomical and physiological dynamics and circuits supporting cognition and executive functions in particular has dramatically increased in recent years. However, its mechanisms of action remain only partially understood.

Objective

In this study we assess the cognitive and physiological effects of anodal tDCS to the DLPFC on executive function in order to understand (1) the role of DLPFC laterality, (2) the physiological dynamics sustaining the modulation of executive function by tDCS, and (3) the impact of state-dependent dynamics.

Methods

In a randomized, placebo-controlled, cross-over study, we applied anodal tDCS targeting the left vs. right DLPFC vs. sham in 20 healthy individuals (10 m

SUBMITTER: Dubreuil-Vall L 

PROVIDER: S-EPMC6851462 | biostudies-literature | 2019 Nov - Dec

REPOSITORIES: biostudies-literature