Successful expansion of community-based drug-resistant TB care in rural Eswatini - a retrospective cohort study.

ABSTRACT:

Objectives

Provision of drug-resistant tuberculosis (DR-TB) treatment is scarce in resource-limited settings. We assessed the feasibility of ambulatory DR-TB care for treatment expansion in rural Eswatini.

Methods

Retrospective patient-level data were used to evaluate ambulatory DR-TB treatment provision in rural Shiselweni (Eswatini), from 2008 to 2016. DR-TB care was either clinic-based led by nurses or community-based at the patient's home with involvement of community treatment supporters for provision of treatment to patients with difficulties in accessing facilities. We describe programmatic outcomes and used multivariate flexible parametric survival models to assess time to adverse outcomes. Both care models were costed in supplementary analyses.

Results

Of 698

SUBMITTER: Kerschberger B 

PROVIDER: S-EPMC6851784 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature