Resting-state brain entropy in right temporal lobe epilepsy and its relationship with alertness.

ABSTRACT:

Background

To date, no functional MRI (fMRI) studies have focused on brain entropy in right temporal lobe epilepsy (rTLE) patients. Here, we characterized brain entropy (BEN) alterations in patients with rTLE using resting-state functional MRI(rs-fMRI) and explored the relationship between BEN and alertness.

Method

Thirty-one rTLE patients and 33 controls underwent MRI scanning to investigate differences in BEN and resting-state functional connectivity (rs-FC) in regions of interest (ROIs) between patients and controls. Correlation analyses were performed to examine relationships between the BEN of each ROI and alertness reaction times (RTs) in rTLE patients.

Results

Compared with controls, the BEN of rTLE patients was significantly increased in the right middle tempo

SUBMITTER: Zhou M 

PROVIDER: S-EPMC6851803 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature