Effect of Vitamin K2 on Postural Sway in Older People Who Fall: A Randomized Controlled Trial.

ABSTRACT:

Objectives

Vitamin K is thought to be involved in both bone health and maintenance of neuromuscular function. We tested the effect of vitamin K2 supplementation on postural sway, falls, healthcare costs, and indices of physical function in older people at risk of falls.

Design

Parallel-group double-blind randomized placebo-controlled trial.

Setting

Fourteen primary care practices in Scotland, UK.

Participants

A total of 95 community-dwelling participants aged 65 and older with at least two falls, or one injurious fall, in the previous year.

Intervention

Once/day placebo, 200 μg or 400 μg of oral vitamin K2 for 1 year.

Measurements

The primary outcome was anteroposterior sway measured using sway plates at 12 months, adjusted for baseline. Secondary

SUBMITTER: Witham MD 

PROVIDER: S-EPMC6851824 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature