Reduction in IBS symptom severity is not paralleled by improvement in quality of life in patients with irritable bowel syndrome.

ABSTRACT:

Background

Irritable bowel syndrome (IBS) is a brain-gut disorder, of which the natural course varies between patients and is difficult to predict. This study aimed to evaluate symptom evolution over a 5-year follow-up period and to identify baseline predictors for symptom severity and quality of life (QoL) at follow-up.

Methods

Maastricht IBS cohort participants completed questionnaires upon inclusion regarding demographics and lifestyle, gastrointestinal (GI) symptoms, anxiety and depression, and QoL. The same questionnaires, in addition to others, were completed after 5 years. Rome criteria were confirmed face-to-face at initial enrollment and through telephonic interviews at follow-up.

Key results

At a mean follow-up of 4.7 years, 379 patients were approached of w

SUBMITTER: Weerts ZZRM 

PROVIDER: S-EPMC6852246 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature