Effect of a gum-based thickener on the safety of swallowing in patients with poststroke oropharyngeal dysphagia.

ABSTRACT:

Background

Increasing viscosity with thickening agents is a valid therapeutic strategy for oropharyngeal dysphagia (OD). To assess the therapeutic effect of a xanthan gum-based thickener (Nutilis Clear^® ) at six viscosities compared with thin liquid in poststroke OD (PSOD) patients.

Methods

A total of 120 patients with PSOD were studied in this controlled, multiple-dose, fixed-order, and single-blind study using videofluoroscopy (VFSS). A series of boluses of 10 mL thin liquid and 2000, 1400, 800, 450, 250, and 150 mPa s viscosities were given in duplicate, interrupted in case of aspiration. We assessed the safety and efficacy of swallow and the kinematics of the swallow response.

Key results

A total of 41.2% patients had safe swallow at thin liquid which s

SUBMITTER: Bolivar-Prados M 

PROVIDER: S-EPMC6852432 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature