Gold(I) Complexes Stabilized by Nine- and Ten-Membered N-Heterocyclic Carbene Ligands.

ABSTRACT: Nine- and ten-membered N-heterocyclic carbene (NHC) ligands have been developed and for the first time their gold(I) complexes were synthesized. The protonated NHC pro-ligands 2 a-h were prepared by the reaction of readily available N,N'-diarylformamidines with bis-electrophilic building blocks, followed by anion exchange. In situ deprotonation of the tetrafluoroborates 2 a-h with tBuOK in the presence of AuCl(SMe₂ ) provided fast access to NHC-gold(I) complexes 3-10. These new NHC-gold(I) complexes show very good catalytic activity in a cycloisomerization reaction (0.1 mol % catalyst loading, up to 100 % conversion) and their solid-state structures reveal high steric hindrance around the metal atom (%V_bur up to 53.0) which is caused by their expanded-ring architectur

SUBMITTER: Cervantes-Reyes A 

PROVIDER: S-EPMC6852534 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature