Automatic quantitative analysis of pulmonary vascular morphology in CT images.

ABSTRACT:

Purpose

Vascular remodeling is a significant pathological feature of various pulmonary diseases, which may be assessed by quantitative computed tomography (CT) imaging. The purpose of this study was therefore to develop and validate an automatic method for quantifying pulmonary vascular morphology in CT images.

Methods

The proposed method consists of pulmonary vessel extraction and quantification. For extracting pulmonary vessels, a graph-cuts-based method is proposed which considers appearance (CT intensity) and shape (vesselness from a Hessian-based filter) features, and incorporates distance to the airways into the cost function to prevent false detection of airway walls. For quantifying the extracted pulmonary vessels, a radius histogram is generated by counting the occu

SUBMITTER: Zhai Z 

PROVIDER: S-EPMC6852650 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature