Dataset Information
Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal Cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Akbari V
PROVIDER: S-EPMC6852802 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Publications
Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal Cancer.
Asian Pacific journal of cancer prevention : APJCP 20190801 8
Background: Colorectal cancer (CRC) is one of the most common cancers worldwide with high number of mortality every year. Microsatellite instability (MSI) is a considerable feature of CRC which affects prognosis and treatment. High level of MSI or MSI-high (MSI-H) colorectal cancer has better prognosis and immunotherapy response, while microsatellite stable (MSS) CRC has better response to 5-fluorouracil (5-FU)-based chemotherapy. More studies are needed, specifically on MSS CRC which has worse ...[more]
