Identification of potential genomic regions and candidate genes for egg albumen quality by a genome-wide association study.

ABSTRACT: Albumen quality is a leading economic trait in the chicken industry. Major studies have paid attention to genetic architecture underlying albumen quality. However, the putative quantitative trait locus (QTL) for this trait is still unclear. In this genome-wide association study, we used an F2 resource population to study longitudinal albumen quality. Seven single-nucleotide polymorphism (SNP) loci were found to be significantly ( p<8.43×10-7 ) related to albumen quality by univariate analysis, while 11 SNPs were significantly ( p<8.43×10-7 ) associated with albumen quality by multivariate analysis. A QTL on GGA4 had a pervasive function on albumen quality, including a SNP at the missense of NCAPG, and a SNP at the intergenic region of FGFPB1. It was further found that the putative QTLs at

SUBMITTER: Qu L 

PROVIDER: S-EPMC6853030 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature