A systematic review of health economic evaluations of proton beam therapy for adult cancer: Appraising methodology and quality.

ABSTRACT:

Background and purpose

With high treatment costs and limited capacity, decisions on which adult patients to treat with proton beam therapy (PBT) must be based on the relative value compared to the current standard of care. Cost-utility analyses (CUAs) are the gold-standard method for doing this. We aimed to appraise the methodology and quality of CUAs in this area.

Materials and methods

We performed a systematic review of the literature to identify CUA studies of PBT in adult disease using MEDLINE, EMBASE, EconLIT, NHS Economic Evaluation Database (NHS EED), Web of Science, and the Tufts Medical Center Cost-Effectiveness Analysis Registry from 1st January 2010 up to 6th June 2018. General characteristics, information relating to modelling approaches, and methodological quali

SUBMITTER: Jones DA 

PROVIDER: S-EPMC6854069 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature