Concentrations and loadings of organophosphate and replacement brominated flame retardants in house dust from the home study during the PBDE phase-out.

ABSTRACT: Polybrominated diphenyl ethers, a class of flame retardants and endocrine disruptors, have been substituted in new products by organophosphate (OPFR) and replacement brominated flame retardants (RBFR). OPFRs and RBFRs readily migrate from consumer products into dust where humans are exposed via incidental ingestion and inhalation. We quantified concentrations and loadings of OPFRs and RBFRs in house dust samples (n?=?317) collected from the homes of Cincinnati women between 2003 and 2006 and examined their associations with demographic and house characteristics. Tris-(1-chloro-2-propyl)-phosphate (TCIPP, geometric mean [GM]: 2140?ng?g^-1, range: 70.1-166,000?ng?g^-1), tris-(1,3-dichloro-2-propyl)-phosphate (TDCIPP, GM: 1840?ng?g^-1, range: 55.2-228,000?ng?g^-1), triphenyl phosphate (TPHP, GM: 1070?ng?g^-1, range: 34.1-62,100?ng?g^-1), 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB, GM: 59.5?ng?g^-1, range: 2.82-7800?ng?g^-1), and bis-(2-ethylhexyl)-tetrabromophthalate (BEH-TEBP, GM: 121?ng?g^-1, range 2.17-13,600?ng?g^-1) were all detected in >90% of dust samples; tris-(2-chloroethyl)-phosphate (TCEP, GM: 669?ng?g^-1, range: 56.8-160,000?ng?g^-1) was detected in 80.1% of samples. Concentrations of EH-TBB and BEH-TEBP increased in house dust from 2003 to 2006. The number of people living in the home, race, education, floor type, and year of sample collection were associated with some OPFR and RBFR concentrations and loadings. This study suggests that OPFRs and RBFRs were ubiquitous in house dust during the PBDE phase-out and justifies more research on the consequences of exposure to these environmental chemicals.

SUBMITTER: Percy Z 

PROVIDER: S-EPMC6854320 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature