Fibroin and Polyvinyl Alcohol Hydrogel Wound Dressing Containing Silk Sericin Prepared Using High-Pressure Carbon Dioxide.

ABSTRACT: Objective: To fabricate and investigate the properties of fibroin and polyvinyl alcohol (PVA) hydrogels containing sericin prepared using high-pressure carbon dioxide (CO₂). Approach: In this study, fibroin/PVA hydrogels with and without sericin were prepared using the high-pressure CO₂ method. The physical and mechanical properties of the hydrogels were investigated using field-emission scanning electron microscopy, Fourier-transform infrared spectroscopy, thermogravimetric analysis, and differential scanning calorimetry, and the swelling, water retention, and compressive properties were assessed. Results: The hydrogels obtained from the combination of fibroin and PVA presented a compositional gradient along the hydrogel thickness and structure.

SUBMITTER: Napavichayanun S 

PROVIDER: S-EPMC6855286 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature