Buruli ulcer treatment: Rate of surgical intervention differs highly between treatment centers in West Africa.

ABSTRACT: BACKGROUND:Antibiotic treatment proved itself as the mainstay of treatment for Buruli ulcer disease. This neglected tropical disease is caused by Mycobacterium ulcerans. Surgery persists as an adjunct therapy intended to reduce the mycobacterial load. In an earlier clinical trial, patients benefited from delaying the decision to operate. Nevertheless, the rate of surgical interventions differs highly per clinic. METHODS:A retrospective study was conducted in six different Buruli ulcer (BU) treatment centers in Benin and Ghana. BU patients clinically diagnosed between January 2012 and December 2016 were included and surgical interventions during the follow-up period, at least one year after diagnosis, were recorded. Logistic regression analysis was carried out to estimate the effect of the

SUBMITTER: Wadagni AC 

PROVIDER: S-EPMC6855495 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature