Ontology highlight
ABSTRACT:
SUBMITTER: Lin J
PROVIDER: S-EPMC6856107 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lin Jianfeng J Zhao Youbao Y Ferraro Aileen R AR Yang Ence E Lewis Zachary A ZA Lin Xiaorong X
Communications biology 20191114
Cellular differentiation is instructed by developmental regulators in coordination with chromatin remodeling complexes. Much information about their coordination comes from studies in the model ascomycetous yeasts. It is not clear, however, what kind of information that can be extrapolated to species of other phyla in Kingdom Fungi. In the basidiomycete <i>Cryptococcus neoformans</i>, the transcription factor Znf2 controls yeast-to-hypha differentiation. Through a forward genetic screen, we iden ...[more]