Heart Rate Variability as a Biomarker of Neurocardiogenic Injury After Subarachnoid Hemorrhage.

ABSTRACT:

Background

The objective of this study was to examine whether heart rate variability (HRV) measures can be used to detect neurocardiogenic injury (NCI).

Methods

Three hundred and twenty-six consecutive admissions with aneurysmal subarachnoid hemorrhage (SAH) met criteria for the study. Of 326 subjects, 56 (17.2%) developed NCI which we defined by wall motion abnormality with ventricular dysfunction on transthoracic echocardiogram or cardiac troponin-I > 0.3 ng/mL without electrocardiogram evidence of coronary artery insufficiency. HRV measures (in time and frequency domains, as well as nonlinear technique of detrended fluctuation analysis) were calculated over the first 48 h. We applied longitudinal multilevel linear regression to characterize the relationship of HRV measure

SUBMITTER: Megjhani M 

PROVIDER: S-EPMC6856427 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature