A 57-Year-Old Woman With Progressive Left Hand Clumsiness and Falls.

ABSTRACT:

Clinical history

A 57-year old woman presented with left hand pain, periodic leg movement during sleep, gradual onset of stiffness, clumsiness, and falls. Neurological examination showed: generalized rigidity and bradykinesia. There was left hand dystonic posturing and ideomotor apraxia, as well as mirror movements of upper limbs and stimulus-sensitive myoclonus. The patient had a high-pitched voice and hypophonia (Video S1).

Discussion

Experts discuss localization and the syndromic diagnosis and predict the underlying pathology. The pathological diagnosis is then provided and clinical learning points are considered.

SUBMITTER: Paramanandam V 

PROVIDER: S-EPMC6856468 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature