Characteristics of atheromatosis in the prediabetes stage: a cross-sectional investigation of the ILERVAS project.

ABSTRACT:

Background

Prediabetes has recently been associated with subclinical atheromatous disease in the middle-aged population. Our aim was to characterize atheromatous plaque burden by the number of affected territories and the total plaque area in the prediabetes stage.

Methods

Atheromatous plaque burden (quantity of plaques and total plaque area) was assessed in 12 territories from the carotid and femoral regions using ultrasonography in 6688 non-diabetic middle-aged subjects without cardiovascular disease. Prediabetes was defined by glycosylated hemoglobin (HbA1c) between 5.7 and 6.4% according to the American Diabetes Association guidelines.

Results

Prediabetes was diagnosed in 33.9% (n = 2269) of the ILERVAS participants. Subjects with prediabetes presented a higher pr

SUBMITTER: Sanchez E 

PROVIDER: S-EPMC6857207 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature