Association of uric acid in serum and urine with subclinical renal damage: Hanzhong Adolescent Hypertension Study.

ABSTRACT:

Background and objectives

The aim of the study was to examine the associations of uric acid (UA) in blood and urine with subclinical renal damage (SRD) and its progression in a Chinese cohort.

Methods

1) 2342 participants from our previously established cohort who were followed up in 2017 were included. Cross-sectional analysis was used to examine the relationships between serum and urinary UA and the risk of SRD. 2) A total of 266 participants were recruited from the same cohort in 2013, and followed up in 2017. Longitudinal analysis was used to determine the relationships of serum and urinary UA with progression of SRD, which was defined as urinary albumin-to-creatinine ratio (uACR) progression or estimated glomerular filtration rate (eGFR) decline.

Results

In cross

SUBMITTER: Wang Y 

PROVIDER: S-EPMC6857911 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature