Prognostic value of des-γ-carboxy prothrombin in patients with hepatocellular carcinoma treated with transarterial chemotherapy: A systematic review and meta-analysis.

ABSTRACT:

Background

Serum des-γ-carboxy prothrombin (DCP) is a hepatocellular carcinoma (HCC) tumor marker that can be used to assess patient prognosis. Since the value of DCP in predicting the prognosis of hepatocellular carcinoma patients treated with transarterial chemotherapy remains controversial, we performed a meta-analysis of previous clinical studies.

Methods

A systematic literature search was performed using PubMed, the MEDLINE database, EMBASE, and the Cochrane Library in accordance with the PRISMA guidelines. The hazard ratio (HR) with 95% confidence interval (CI) was used to estimate the effect size.

Results

Six respective cohort studies including a total of 943 cases were identified. The pooled results showed that low DCP was associated with a favorable overall s

SUBMITTER: Yang M 

PROVIDER: S-EPMC6857949 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature