Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial.

ABSTRACT:

Introduction

Weaning from ventilation is a complex process involving several stages that include recognition of patient readiness to begin the weaning process, steps to reduce ventilation while optimising sedation in order not to induce distress and removing the endotracheal tube. Delay at any stage can prolong the duration of mechanical ventilation. We developed a multicomponent intervention targeted at helping clinicians to safely expedite this process and minimise the harms associated with unnecessary mechanical ventilation.

Methods and analysis

This is a 20-month cluster randomised stepped wedge clinical and cost-effectiveness trial with an internal pilot and a process evaluation. It is being conducted in 18 paediatric intensive care units in the UK to evaluate a protoco

SUBMITTER: Blackwood B 

PROVIDER: S-EPMC6858098 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature