Perineural local anaesthetic catheter after major lower limb amputation trial (PLACEMENT): results from a randomised controlled feasibility trial.

ABSTRACT:

Objectives

To determine the feasibility of undertaking a randomised controlled effectiveness trial evaluating the use of a perineural catheter (PNC) after major lower limb amputation with postoperative pain as the primary outcome.

Design

Randomised controlled feasibility trial.

Setting

Two vascular Centres in South Wales, UK.

Participants

50 patients scheduled for major lower limb amputation (below or above knee) for complications of peripheral vascular disease.

Interventions

The treatment arm received a PNC placed adjacent to the sciatic or tibial nerve at the time of surgery, with continuous infusion of levobupivacaine hydrochloride 0.125% for up to 5 days. The control arm received neither local anaesthetic nor PNC. Both arms received usual perioperati

SUBMITTER: Bosanquet DC 

PROVIDER: S-EPMC6858124 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature