Observational study comparing the accuracy/variability between the ERSPC and the PCPT risk calculators for the prediction of significant prostate cancer in patients with PSA <10 ng/mL.

ABSTRACT: INTRODUCTION:Risk calculators (RCs) are easy-to-use tools considering available clinical variables that could help to select those patients with risk of prostate cancer (PCa) who should undergo a prostate biopsy. OBJECTIVE:To perform a comparison for the prediction of significant PCa (SigPCa) between the European Randomised Study of Screening for PCa (ERSPC) and the PCa Prevention Trial (PCPT) RCs in patients with prostate-specific antigen (PSA) between 3 and 10 ng/mL through an evaluation of the accuracy/variability between two consecutive PSA values. SETTING:An observational study in a major university hospital in the south of Spain. METHODS AND PARTICIPANTS:An observational study was performed in patients who underwent a prostate biopsy. SigPCa probabilities were calculated with the two

SUBMITTER: Gomez Gomez E 

PROVIDER: S-EPMC6858159 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature