Benefit of carotid revascularisation for women with symptomatic carotid stenosis: protocol for a systematic review.

ABSTRACT: INTRODUCTION:Carotid intervention in the form of endarterectomy or stenting is the current standard of care for the majority of patients with symptomatic high-grade carotid stenosis. However, some randomised controlled trials (RCT) have demonstrated that women benefited significantly less from intervention than men. It is unclear if this is a true phenomenon or a study sampling artefact, as women were severely under-represented in all RCTs of carotid revascularisation. A systematic review is needed to summarise the existing data and to answer the question of whether a women-only trial for symptomatic patients with ipsilateral carotid stenosis is scientifically necessary and ethically permissible. METHODS AND ANALYSIS:We will systematically search Medline, Embase, PubMed and the Cochrane li

SUBMITTER: Bereznyakova O 

PROVIDER: S-EPMC6858193 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature