Effects on renal outcome of concomitant acute pyelonephritis, acute kidney injury and obstruction duration in obstructive uropathy by urolithiasis: a retrospective cohort study.

ABSTRACT:

Objective

Obstruction release from urolithiasis can be delayed with a lack of suggested time for preventing the deterioration of renal function. The objective of this study was to investigate the effect of obstruction duration, concomitant acute kidney injury (AKI) or acute pyelonephritis (APN) during the obstruction on the prognosis of renal function.

Design

Retrospective cohort study.

Setting and participants

1607 patients from a urolithiasis-related obstructive uropathy cohort, between January 2005 and December 2015.

Outcome measures

Estimated glomerular filtration rate (eGFR) decrease ≥30% and/or end-stage renal disease (ESRD), and eGFR decrease ≥50% and/or ESRD, according to obstruction duration, AKI and APN accompanied by obstructive uropathy.

Results<

SUBMITTER: Lee EH 

PROVIDER: S-EPMC6858199 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature