Diagnosed prevalence of Ehlers-Danlos syndrome and hypermobility spectrum disorder in Wales, UK: a national electronic cohort study and case-control comparison.

ABSTRACT:

Objectives

To describe the epidemiology of diagnosed hypermobility spectrum disorder (HSD) and Ehlers-Danlos syndromes (EDS) using linked electronic medical records. To examine whether these conditions remain rare and primarily affect the musculoskeletal system.

Design

Nationwide linked electronic cohort and nested case-control study.

Setting

Routinely collected data from primary care and hospital admissions in Wales, UK.

Participants

People within the primary care or hospital data systems with a coded diagnosis of EDS or joint hypermobility syndrome (JHS) between 1 July 1990 and 30 June 2017.

Main outcome measures

Combined prevalence of JHS and EDS in Wales. Additional diagnosis and prescription data in those diagnosed with EDS or JHS compared with matc

SUBMITTER: Demmler JC 

PROVIDER: S-EPMC6858200 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature