Effects of obesity and a history of gestational diabetes on the risk of postpartum diabetes and hyperglycemia in Chinese women: Obesity, GDM and diabetes risk.

ABSTRACT:

Objective

To evaluate the independent or combined effects of gestational diabetes (GDM) and pre-pregnancy and postpartum BMI on the odds of postpartum diabetes and hyperglycemia.

Methods

The study samples included 1263 women with prior GDM and 705 women without GDM. Postpartum 1-7 years diabetes was diagnosed by the standard oral glucose tolerance test.

Results

The multivariable-adjusted odds ratios among women with prior GDM, compared with those without it, were 7.52 for diabetes and 2.27 for hyperglycemia. The multivariable-adjusted odds ratios at different postpartum BMI levels (<24, 24-27.9, and ≥ 28 kg/m²) were 1.00, 2.80, and 8.08 for diabetes (P_trend < 0.001), and 1.00, 2.10, and 4.42 for hyperglycemia (P_trend < 0.001), respecti

SUBMITTER: Fan Y 

PROVIDER: S-EPMC6858564 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature