Association of 5-lipoxygenase activating protein gene polymorphism and stroke: A study from north east of Iran.

ABSTRACT: Background: Stroke is a multifactorial disorder and a major cause of morbidity and mortality around the world. There are growing numbers of candidate gene pathways which are thought to be associated with stroke. Genes involved in lipid metabolism are important issues in stroke studies. Studying different polymorphisms in these genes are becoming an interest for researchers. 5-lipoxygenase activating protein (ALOX5AP) is one of these genes. Different studies have provided different relations between ALOX5AP promoter polymorphism (rs17222919) and stroke. In the present study, we have evaluated this gene polymorphism in a population in north east of Iran. Methods: This case-control study took place in Ghaem Hospital, Mashhad, Iran. Patients with computed tomography (CT) or magne

SUBMITTER: Erfani M 

PROVIDER: S-EPMC6858598 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature