Molecular characterization of three intestinal protozoans in hospitalized children with different disease backgrounds in Zhengzhou, central China.

ABSTRACT:

Background

Cryptosporidium spp. and Giardia duodenalis are major intestinal pathogens that can cause diarrheal diseases in humans, especially children. Enterocytozoon bieneusi is another parasite which can cause gastrointestinal tract disorders, with diarrhea being the main clinical symptom. However, few genetic studies of these parasites in pediatric inpatients in China have been published.

Methods

To assess the genetic characteristics and epidemiological status of these parasites, a total of 2284 fecal samples were collected from children in the pediatric departments of three hospitals in Zhengzhou, central China, and screened for these protozoans with PCR, based on the small subunit ribosomal RNA (SSU rRNA) genes of Cryptosporidium spp. and G. duodenalis and the internal

SUBMITTER: Yu F 

PROVIDER: S-EPMC6858702 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature