Associative conditioning remaps odor representations and modifies inhibition in a higher olfactory brain area.

ABSTRACT: Intelligent behavior involves associations between high-dimensional sensory representations and behaviorally relevant qualities such as valence. Learning of associations involves plasticity of excitatory connectivity, but it remains poorly understood how information flow is reorganized in networks and how inhibition contributes to this process. We trained adult zebrafish in an appetitive odor discrimination task and analyzed odor representations in a specific compartment of the posterior zone of the dorsal telencephalon (Dp), the homolog of mammalian olfactory cortex. Associative conditioning enhanced responses with a preference for the positively conditioned odor. Moreover, conditioning systematically remapped odor representations along an axis in coding space that represented attractiven

SUBMITTER: Frank T 

PROVIDER: S-EPMC6858881 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature